International orthopaedics
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We investigated the role of human platelet gel (PG) embedded within gelatin (Gel) scaffold on healing of critical-sized radial bone defects in rats. ⋯ Human PG had beneficial effects on bone regeneration, while combination of PG and Gel had no remarkable beneficial effect. Therefore, PG when used alone can be regarded as a promising osteoinductive and osteoconductive option in bone tissue engineering applications.