Clinical therapeutics
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Clinical therapeutics · Jan 2012
Adherence to statin treatment and health outcomes in an Italian cohort of newly treated patients: results from an administrative database analysis.
Adherence to statin treatment is expected to be associated with health outcomes. Much of the available evidence is derived from studies conducted on selected populations (eg, Medicaid population), on specific cohorts of patients (eg, patients with diabetes mellitus or those who have experienced acute myocardial infarction [AMI]), or with respect to a single outcome (eg, only death or only AMI). ⋯ In this Italian cohort of newly treated patients, suboptimal adherence to statins occurred in a substantial proportion of patients and was associated with increased risk of adverse health outcomes.
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Clinical therapeutics · Jan 2012
Symptomatic management of fever by Swiss board-certified pediatricians: results from a cross-sectional, Web-based survey.
Symptomatic management is often all that is recommended in children with fever. To date, only 2 nationwide surveys of pediatricians regarding their attitudes toward fever have been published. ⋯ Based on the findings from the present survey, antipyretics are often prescribed to treat the general discomfort that accompanies fever. Nonetheless, a gap exists between available evidence and clinical practice. Guidelines should take this fact into account.