Clinical therapeutics
-
Clinical therapeutics · Jul 2012
Risk of hemorrhage and treatment costs associated with warfarin drug interactions in patients with atrial fibrillation.
Drug interactions with warfarin are common and may be responsible for increased patient morbidity and treatment costs. ⋯ Warfarin-potentiating drugs were commonly used among AF patients on warfarin. The use of potentiating drugs increased the risk of a hemorrhage, leading to higher treatment costs. More frequent monitoring or alternative anticoagulant therapies are needed to avoid frequent warfarin drug interactions.