Revista de neurologia
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Revista de neurologia · Jun 2005
Clinical Trial[Effectiveness and safety of oxcarbazepine in chronic neuropathic pain: a study of 40 cases].
Neuropathic pain (NP) often fails to respond to the commonly established analgesic treatment. This fact, together with the existence of side effects, has led to the need to evaluate the analgesic effectiveness of antiepileptic drugs, which, as in the case of oxcarbazepine (OXC), are a valid alternative. ⋯ OXC can be seen as a therapeutic alternative to be taken very much into account in patients with NP having different aetiologies; it has a good benefit-risk ratio and is a form of treatment that is well accepted by patients.
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Revista de neurologia · Jun 2005
[Evaluation of the diagnostic value of a Spanish adaptation of the Buschke Memory Impairment Screen in the detection of dementia and cognitive impairment].
Screening tests for dementia are a fundamental tool in specialist consultation and primary care. The instruments currently used are time-consuming and the diagnostic performance they offer is rather poor. The original version of the Buschke Memory Impairment Screen (MIS) is a quick simple test with high discriminatory power. ⋯ This version of the Buschke MIS offers a high level of discriminatory power both for dementia and for CD, as well as an adequate degree of inter and intraobserver reliability within the context of a specialist consultation. Because it is quick (less than 4 minutes) and simple to administer, MIS represents a reasonable alternative to other screening methods.
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Revista de neurologia · Jun 2005
[Analysis of the headaches treated in emergency neurology departments].
Headache is the main cause of visits to the emergency neurology department at our hospital. We perform a descriptive analysis of the patients who visited the Emergency department because of this pathology and who required neurological assessment according to the International Headache Society's new classification of headaches. ⋯ The percentage of secondary headaches that were diagnosed thanks to the presence of an on-call neurologist is very high: 13.36% of the evaluations requested. The headaches that most frequently require evaluation are generally the most prevalent: migraine without aura and tension-type headache. The presence of an on-call neurologist reduces the number of patients admitted to hospital because of this pathology by over 50%.
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Revista de neurologia · May 2005
Review[Clinical experiences with pregabalin in the treatment of focal epilepsies].
Pregabalin is an antiepileptic drug recently approved in the European Union for add-on therapy of focal epilepsy. A review of its clinical and pharmacological characteristics is, therefore, appropriate. ⋯ Pregabalin favourable pharmacokinetic profile, in addition to its good tolerability and remarkable efficacy make this new antiepileptic drug an attractive option for the treatment of focal epilepsies.
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Shaken baby syndrome (SBS) is a form of physical abuse that includes the presence of a subdural or subarachnoid haematoma or diffuse cerebral oedema, retinal haemorrhages and, in general, absence of other physical signs of traumatic injury. Osteogenesis imperfecta (OI) is a genetic disorder affecting the synthesis of type I collagen that leads to brittle bones with frequently occurring fractures, with presenting clinical symptoms taking a variety of forms. A differential diagnosis allowing it to be distinguished from physical abuse is known, due to the existence of bone fractures with no known traumatic injuries, but we do not understand the link between OI and SBS. ⋯ The suspected existence of SBS is unpleasant both for the health care professional and for the patient's relatives. The existence of rib fractures in an obvious case of shaken baby syndrome suggested malicious abuse; however, the parents' attitude and the existence of OI made us think that no harm was intended. Shaking could have been secondary to bouts of crying due to microfissures related to the OI. The differential diagnosis of processes that can be mistaken for shaken baby or from favourable or predisposing medical factors must be taken into consideration.