Annals of neurology
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Annals of neurology · Dec 2014
Randomized Controlled TrialMendelian randomization of serum urate and parkinson disease progression.
Higher serum urate concentrations predict more favorable prognosis in individuals with Parkinson disease (PD). The purpose of this study was to test the causality of this association using a Mendelian randomization approach. ⋯ This Mendelian randomization analysis adds to the evidence of a causal protective effect of high urate levels.