Seminars in perinatology
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Seminars in perinatology · Oct 2002
ReviewHospital-acquired infections in the neonatal intensive care unit--Klebsiella pneumoniae.
Klebsiella pneumoniae is medically the most important organism of the Klebsiella species. It is responsible for a significant proportion of hospital-acquired infections including septicemias, urinary tract infections, pneumonia, and soft tissue infections especially in the immunocompromised hosts such as the neonate. ⋯ The problems associated with extended spectrum beta-lactamase-producing organisms include difficulties in accurate antimicrobial susceptibility testing, limited treatment options and increased morbidity and perhaps mortality. Hence, prevention through implementation of strict infection control guidelines, effective hand washing and judicious use of antimicrobials such as third generation cephalosporins is important to effectively reduce the morbidity associated with this infection.
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Seminars in perinatology · Apr 2002
ReviewEpidural analgesia: effects on labor progress and maternal and neonatal outcome.
The intended and unintended effects of epidural labor analgesia are reviewed. Mothers randomized to epidural rather than parenteral opioid analgesia have better pain relief. Fetal oxygenation is not affected by analgesic method; however, neonates whose mothers received intravenous or intramuscular opioids rather than epidural analgesia require more naloxone and have lower Apgar scores. ⋯ Epidural analgesia has no affect but intrapartum opioids decrease lactation success. Epidural use and urinary incontinence are weakly, but probably not causally, associated. Epidural labor analgesia would improve if the mechanisms of these unintended effects could be determined.
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Several new techniques and medications are available for epidural labor analgesia. Two significant additions are ropivacaine and levobupivacaine. ⋯ The clinical implications of patient controlled epidural analgesia and ambulatory epidural techniques are discussed. The controversies surrounding epidural test dose and fluid preloading are examined.
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Seminars in perinatology · Apr 2002
ReviewAnesthesia for nonobstetric surgery in the pregnant patient.
Each year over 75,000 pregnant women in the United States undergo nonobstetric surgery. The operations include those directly related to pregnancy, such as cerclage, those indirectly related to pregnancy, such as ovarian cystectomy, and those unrelated to gestation, such as appendectomy. When a pregnant woman presents for surgery, it is a stressful event for everyone involved. ⋯ This article reviews the physiologic and anatomic changes that affect anesthetic care during pregnancy. The author also reviews the effects of anesthetic drugs and perioperative events on the fetus and on the pregnancy outcome. The relatively small number of published series are reviewed as well as the controversial recommendations regarding fetal and maternal monitoring during surgery.
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Seminars in perinatology · Apr 2002
ReviewCombined spinal-epidural analgesia for labor: breakthrough or unjustified invasion?
The combined spina-epidural (CSE) technique has become increasingly popular for labor analgesia. The advantages of the CSE include more rapid onset of analgesia, reduced total drug dosage, minimal or no motor blockade, and increased patient satisfaction. ⋯ Despite these potential advantages, the indications for CSE versus epidural analgesia remain unclear and controversial. This review should allow better understanding of the benefits and risks of this technique, and bearing in mind that no ultimate neuraxial analgesic exists, it would seem that CSE should be considered a major breakthrough in the management of labor analgesia.