Neurosurgery
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This is the largest contemporary series examining long-term clinical and angiographic follow-up of unclippable wrapped intracranial aneurysms. ⋯ Wrapping or clip-wrapping of unclippable intracranial aneurysms is safe and seems to confer protection against aneurysmal growth or subarachnoid hemorrhage.
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Biography Historical Article
An essay concerning human understanding: how the cerebri anatome of Thomas Willis influenced John Locke.
Neurosurgeons are familiar with the anatomic investigations of Thomas Willis, but his intellectual legacy actually extends into the arena of philosophy. John Locke was a student of Willis while at Oxford, and this essay explores how some of Willis's anatomic discoveries might have influenced the ideas Locke expressed in his Essay Concerning Human Understanding. It also includes historical information about 17th century England and the group of men (including Christopher Wren and Robert Boyle) who worked with Willis and founded the Oxford Experimental Philosophy Club, which became the Royal Society.
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Comparative Study
Retractable self-expandable stent for endovascular treatment of wide-necked intracranial aneurysms: preliminary experience.
Intracranial stenting combined with endosaccular coiling is a therapeutic alternative for the endovascular treatment (EVT) of wide-necked intracranial aneurysms. The current limitation of available stents is the impossibility to reposition them once they are partially deployed. Recently, the first retractable self-expandable stent has been developed and we sought to evaluate the use of this stent for EVT of wide-necked intracranial aneurysms. ⋯ The Leo stent appears very useful for EVT of wide-necked intracranial aneurysms. The advantage of this stent is the possibility to reposition it which allows a very precise positioning across the aneurysm neck.
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Neurocognitive dysfunction has been shown to occur in roughly 25% of patients undergoing carotid endarterectomy (CEA). Despite this, little is known about the mechanism of this injury. Recently, several groups have shown that new diffusion weighted imaging (DWI)-positive lesions are seen in 20% of patients undergoing CEA. We investigated to what degree neurocognitive dysfunction was associated with new DWI lesions. ⋯ Neurocognitive dysfunction after CEA does not seem to be associated with new DWI positive lesions.