Neurosurgery
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Multicenter Study
Preconditioning effect on cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Recent experimental evidence indicates that endogenous mechanisms against cerebral vasospasm can be induced via preconditioning. ⋯ This retrospective case-control study suggests that endogenous protective mechanisms against cerebral vasospasm-a preconditioning effect-may exist in humans, although these results could be the effect of atherosclerosis or some combination of preconditioning and atherosclerosis. Additional studies investigating the potential of preconditioning in aneurysmal subarachnoid hemorrhage are warranted.