Neurosurgery
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Optimal doses for single-fraction stereotactic radiosurgery (SRS) in the treatment of brain metastases are not well established. Our institution utilized conservative dosing compared to maximum-tolerated doses from the Radiation Therapy Oncology Group 90-05 Phase I study. ⋯ Histology predicts LC after conservative SRS doses with evidence of a dose-response relationship. Conservative single-fraction SRS doses confer minimal toxicity and acceptable control in certain subgroups (breast cancer, <5 mm), with suboptimal control in larger lesions and in combination with whole brain radiation therapy.
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Pediatric hydrocephalus represents a high health care burden in the United States (US). Surgery is the mainstay of treatment. ⋯ There was no significant effect on time to failure between patients undergoing ETV and shunt, except in infants' age <1 yr.