Irish journal of medical science
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Review Meta Analysis
Increased leptin levels in patients with rheumatoid arthritis: a meta-analysis.
Published data regarding the association of leptin levels with rheumatoid arthritis (RA) are contradictory. To derive a more precise estimation of this relationship, a meta-analysis was performed. ⋯ The present meta-analysis suggested that leptin levels were higher in RA patients than those in healthy controls, which may be subject to different region, race, age, BMI, disease duration and disease activity.
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Randomized Controlled Trial Comparative Study
Evaluation of the effect of intra-operative intravenous fluid on post-operative pain and pulmonary function: a randomized trial comparing 10 and 30 ml kg(-1) of crystalloid.
Existing evidence suggests that administration of intravenous fluids has been shown to improve outcomes including pain in gynecological laparoscopic surgery but the optimum fluid dose has not been determined. ⋯ Liberal compared to restrictive administration of i.v. crystalloid is associated with a clinical modest reduction in pain. Pulmonary dysfunction was not increased with liberal fluid administration.
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The Growing Up in Ireland Infant Cohort dataset (n = 11,134) includes information on fertility treatments for over 400 infants. IVF (28.1 %) and IVF-related treatments (17.8 %) were the most frequent, but there was also a high percentage following clomiphene citrate alone (31.5 %). Infants born following fertility treatment were much more likely to be in higher income families, and this relationship was not accounted for by older mothers in wealthier families. Analysis of fertility-treatment pregnancies among Irish infants, controlling for income and maternal age, shows a greater risk of multiple birth and low birth-weight, although the latter appears to be largely related to the former especially for IVF-type treatments.