Irish journal of medical science
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Emergency department (ED) boarders, namely patients who have been admitted under an in-patient service but remain on a trolley in the ED, have long been a problem in the Irish healthcare system. ⋯ Discrepancies in coding of ED boarders may result in significant revenue losses for certain hospitals.
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Intrathecal opioid administration yields high quality analgesia with an associated low incidence of side effects and complication. The benefits of spinal "opioid only technique" include absence of neuronal blockade, infusion pump malfunction and sympathetic blockade. This technique declined after serious side effects were reported in the 1990s. ⋯ Intrathecal morphine for post-op analgesia is efficacious and safe in a post-thoracotomy population.
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The Runx family proteins, including RUNX3, are tissue-restricted transcription factors and play role in neuronal development and tumorigenesis. RUNX3 has an important role in glioblastoma (GBM) tumorigenesis because of its promoter hypermethylation. ⋯ This study overemphasized the RUNX3 gene importance in brain tumors, due to the existence of at least one methylated allele.
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Evaluation of a new systems-based curriculum in an undergraduate Irish Medical School was carried out with the validated Dundee Ready Educational Environment (DREEM) inventory. Comparison was made with the results from a previous DREEM study in the old curriculum. ⋯ DREEM is a valuable tool in evaluating the educational environment and monitoring the impact of curricular change.