Irish journal of medical science
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Meta Analysis Comparative Study
Are beta-blockers effective for preventing post-coronary artery bypass grafting atrial fibrillation? Direct and network meta-analyses.
Atrial fibrillation is the most common arrhythmia in clinical practice and is a major contributor to mortality. Recently, several studies have reported different results for treatments aimed at reducing the risk of postoperative AF. ⋯ The network meta-analysis revealed no significant differences among eight types of BB treatments but did provide a ranking. BB treatments could significantly reduce the occurrence of post-CABG AF. Insufficient evidence was available to show that one BB treatment was more effective than the others were. According to our network meta-analysis, bisoprolol and landiolol+bisoprolol are better alternatives compared with the other treatments.
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Continuous subcutaneous insulin pump therapy (CSII or pump therapy) is a well-recognised treatment option for Type 1 diabetes mellitus (T1DM) in paediatrics. It is especially suited to children because it optimises control by improving flexibility across age-specific lifestyles. The NICE guidelines (2008) recognise that pump therapy is advantageous and that it should be utilised to deliver best practice. In Ireland, the National Clinical Program for Diabetes will increase the availability and uptake of CSII in children and thus more clinicians are likely to encounter children using CSII therapy. ⋯ This review addresses the principles of insulin pump management in children which all health care professionals involved in caring for the child with diabetes, shoud be familiar with.
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Posterior spinal instrumentation and fusion for correction of adolescent idiopathic scoliosis (AIS) typically requires lengthy operating time and may be associated with significant blood loss and subsequent transfusion. This study aimed to identify factors predictive of duration of surgery, intraoperative blood loss and transfusion requirements in an Irish AIS cohort. ⋯ Larger preoperative curve magnitudes in AIS increase operative time and intraoperative blood loss; preoperative Cobb angles greater than 70(o) and intraoperative blood loss greater than 1400 ml are predictive of red blood cell transfusion requirement in this patient group.
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Biography Historical Article
Wilde's worlds: Sir William Wilde in Victorian Ireland.
Other contributors to this collection have evoked the disparate worlds inhabited by Sir William Wilde. ⋯ A variety of close British Isles parallels can be drawn between Wilde and his cohort in the medical elite of Dublin and their clinical peers in Edinburgh and London both in terms of clinical practice and self-presentation and in terms of the social and political challenges facing their respective ancient regime hegemonies in an age of democratic radicalisation. The shared ideological interests of Wilde and his cohort, however, were also challenged by the socio-political particularities and complexities of Ireland during the first half of the nineteenth century culminating in the catastrophe of the Great Famine. William Wilde saw the practice of scientific medicine as offering a means of deliverance from historical catastrophe for Irish society and invoked a specifically Irish scientific and medical tradition going back to the engagement with the condition of Ireland by enlightened medical men in the seventeenth and eighteenth centuries.
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Biography Historical Article
Sir William Wilde and provision for the blind in nineteenth-century Ireland.
As Assistant Commissioner for the Census of Ireland Sir William Wilde worked as an early epidemiologist, providing information regarding the deaf-and-dumb and the blind in mid-nineteenth-century Ireland. As a social agitator he focussed the attention of the authorities to the plight of the blind and their inability to earn a living and support themselves. This paper highlights his contribution to the provision for the blind in Ireland.