Irish journal of medical science
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A difficult question in autopsy practice is whether intracranial haemorrhage has resulted from or brought about a fall. ⋯ We are of the view that a comprehensive analysis of fatal falls with intracranial haemorrhage warrants a detailed neuropathologic examination as part of the overall death analysis.
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Neuroendocrine neoplasm of GIT (gastrointestinal tract) and pancreas is heterogenous with variable clinical features and disease outcomes. Despite multiple attempts of risk stratification by grading and staging, some have unpredictable clinical courses. Well-differentiated grade 3 neuroendocrine tumour (G3NET) is a recent subcategory introduced in the 2019 WHO classification based on morphology, molecular profile and prognosis distinguishing it from neuroendocrine carcinoma(NEC). This study aimed at describing the spectrum of NENs encountered in a tertiary centre with focus on reclassifying previously reported G3 tumours into G3 NET and NEC and comparing the survival between them. ⋯ Grading of NEN is vital for therapeutic decisions and for prognostication. Currently, morphology is the key to recognise the well-differentiated G3 NETs, but can be subject to interobserver variability. Molecular surrogates may play a role in accurately identifying these entities, the validity of which is warranted.
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Polycystic ovary syndrome is the most extensive type of reproductive endocrine disease in department of gynecology. ⋯ Serum EMAb level in PCOS patients with infertility was significantly increased, and it was significantly correlated with sex hormone levels. Serum EMAb level could be used as a predictor of infertile patients with PCOS.
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Many cycling collisions occur due to human error, cycling ability, distraction or infrastructure. One such infrastructural issue for cyclists sharing the road with tram lines is where the wheel of the bicycle gets caught in the rail track itself or in a gap between the rail and the road margin resulting in a sudden stall of the bicycle and potentially significant injury. This study aims to describe the crash characteristics of tram-track cycling collisions and their associated injuries. ⋯ Further prospective multi-centre studies are required to properly describe the magnitude cycling accidents around the Luas tracks and inform future public health measures in this area.
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Preoperative anxiety is a challenging problem in the preoperative care of patients. Identifying risk factors helps nurses provide psychological support during the pre-operative visit so that stress can be reduced. ⋯ The importance of surgical anxiety for the health system, which affects two out of every three hospitalized patients, should not be underestimated. Therefore, national and global plans should be made to prevent and manage surgical anxiety.