Irish journal of medical science
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Review Meta Analysis
The use of radiomic analysis of magnetic resonance imaging findings in predicting features of early osteoarthritis of the knee-a systematic review and meta-analysis.
The primary aim of this study was to systematically review current literature evaluating the use of radiomics in establishing the role of magnetic resonance imaging (MRI) findings in native knees in predicting features of osteoarthritis (OA). A systematic review was performed with respect to PRISMA guidelines in search of studies reporting radiomic analysis of magnetic resonance imaging (MRI) to analyse patients with native knee OA. Sensitivity and specificity of radiomic analyses were included for meta-analysis. Following our initial literature search of 1271 studies, only 5 studies met our inclusion criteria. ⋯ Meta-analysis demonstrated the pooled sensitivity and specificity for MRI in predicting features of OA in patients with native knees were 0.74 (95% CI 0.71, 0.78) and 0.85 (95% CI 0.83, 0.87), respectively. The results of this systematic review suggest that the high sensitivities and specificity of MRI-based radiomics may represent potential biomarker in the early identification and classification of native knee OA. Such analysis may inform surgeons to facilitate earlier non-operative management of knee OA in the select pre-symptomatic patients, prior to clinical or radiological evidence of degenerative change.
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Review Case Reports
A case series of musical hallucinations in psychiatry of old age-in search of the sound of silence.
Musical hallucinations (MH) are the subjective experience of hearing music when none is played. They are a rare, understudied area of psychiatry. MH are more common in women and older age and have several underlying aetiologies and predisposing factors such as hearing impairment, mental illness and certain medications. ⋯ One case had a swift resolution of symptoms with a combination of an antipsychotic and antidepressant. The other two cases had limited responses to treatment despite optimising their hearing aids and trials of a number of medications at therapeutic levels. Further research into MH is needed to establish a treatment that is evidence based and symptom focused.
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Endometriosis is the leading cause of chronic pelvic pain in women of reproductive age with debilitating effects on quality of life, yet no cure exists. Exercise yields the potential in providing women with a non-invasive, non-pharmacological method of symptom control. ⋯ For clinicians to incorporate exercise in managing endometriosis, clear recommendations regarding advice and benefits are needed.
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This systematic review and meta-analysis aimed to assess the effectiveness of nurses' psychosocial interventions for addressing sensory deprivation in intensive care units (ICUs). ⋯ In conclusion, psychosocial interventions aimed at reducing sensory deprivation in intensive care units exert beneficial effects on individuals, notably enhancing their level of consciousness and improving sleep quality.
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There is a paucity of research reporting the long-term outcomes of older adults who have completed geriatric rehabilitation following COVID-19. ⋯ Multidisciplinary rehabilitation for older adults with acute COVID-19 infection can assist patients to return to their premorbid functional ability. On discharge from rehabilitation, ongoing follow-up of older adults is recommended to assist them to negotiate and manage ongoing symptomatology such as breathlessness or fatigue.