The Veterinary record
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The Veterinary record · Aug 2014
Randomized Controlled TrialContinuous infusion of remifentanil combined with target-controlled infusion of propofol for tracheal intubation in dogs.
Ninety dogs presenting for elective surgery were randomly assigned into three groups of 30. Intubation conditions, haemodynamic responses and other events were evaluated following target controlled infusion (TCI) with propofol at 3.0 μg/ml, combined with variable infusion rates of remifentanil (R1 0.1 μg/kg/minute, R2 0.2 μg/kg/minute, R3 0.3 μg/kg/minute). Tracheal intubation was recorded as excellent, good or poor according to jaw relaxation, tongue withdrawal, ease of laryngoscopy, swallowing, coughing and limb movement. ⋯ Following intubation, despite an increase in MAP and MHR values, they remained significantly lower than baseline values. Muscle twitching and involuntary movement was observed after propofol induction in 10 dogs. The results suggest that a plasma concentration of 3 μg/ml propofol along with an infusion rate of remifentanil at 0.3 μg/kg/minute may provide satisfactory conditions for intubation, while avoiding major adverse haemodynamic effects.
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The Veterinary record · Dec 2013
Randomized Controlled TrialDifferent volumes of injectate using electrostimulator and blinded techniques for brachial plexus block in dogs.
To compare different volumes of injectate using electrostimulator (ES)-guided and blind brachial plexus blockade (BPB) techniques in dogs. Prospective, randomised, blinded study. Fifty-eight healthy adult purpose-bred beagle dogs. ⋯ When an ES is not available, the blind technique with 1 ml/kg is also acceptable. However, when performing an ES-guided BPB, volumes as low as 0.2 ml/kg can be used. As volume is increased, the musculocutaneous nerve becomes more likely to be targeted.
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The Veterinary record · Dec 2013
Randomized Controlled TrialThe effects of subarachnoid administration of hyperbaric solutions of bupivacaine or ropivacaine in xylazine-sedated calves undergoing surgery.
The aim of this study was to compare the effects of subarachnoid administration of hyperbaric solutions of bupivacaine or ropivacaine in xylazine-sedated calves undergoing surgery. Subarachnoid anaesthesia was performed with either 20 mg of hyperbaric bupivacaine (bupivacaine group (BG), n=10) or 30 mg of hyperbaric ropivacaine (ropivacaine group (RG), n=10) into the lumbar dural space of 20 calves in a randomised, prospective clinical trial. Systolic (SBP), diastolic (DBP) and mean (MBP) blood pressure, heart rate (HR), respiratory rate, rectal temperature were recorded after sedation (time 0), and up to 120 minutes after injection. ⋯ Onset of anaesthesia (mean±sd; BG, 5±1 minutes; RG, 7±1 minutes) and duration of anaesthesia (mean±sd; BG, 153±32 minutes; RG, 86±12 minutes) were significantly different between groups. Analgesic scores were significantly higher than baseline from 5 to 120 min, and from 7 to 85 min in BG and RG, respectively. Subarachnoid administration of hyperbaric solutions of bupivacaine produced faster onset and longer duration of anaesthesia than ropivacaine.
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The Veterinary record · Jun 2009
Randomized Controlled TrialMechanical ventilation of six dogs anaesthetised with isoflurane or sevoflurane delivered by a Komesaroff anaesthetic machine.
After intravenous induction, six beagles were connected to a Komesaroff machine provided with a single in-circuit vaporiser and ventilated mechanically at either nine or 14 breaths/minute while anaesthetised with either isoflurane or sevoflurane. The vaporiser was initially set at position 4/4 (fully open) and the anaesthetic concentrations were measured after one and five minutes; the vaporiser was then set at the lowest setting able to maintain anaesthesia. Cardiorespiratory variables were measured throughout the study. In most cases anaesthesia was maintained at setting 1/4 with isoflurane and at setting 1.5/4 or 2/4 with sevoflurane.
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The Veterinary record · Aug 2007
Randomized Controlled TrialRecovery characteristics following maintenance of anaesthesia with sevoflurane or isoflurane in dogs premedicated with acepromazine.
A standard anaesthetic protocol was used to anaesthetise 40 dogs for intravenous urography and a retrograde urethrogram or vaginourethrogram. The dogs were allocated by blocked randomisation to receive either isoflurane or sevoflurane for maintenance of anaesthesia after they had been premedicated with acepromazine and pethidine, and anaesthesia induced with propofol. ⋯ The scores for ataxia were significantly lower after 60 minutes than after 30 minutes, but there was no significant difference between the groups. The quality of recovery was significantly better in the dogs that received sevoflurane than in those that received isoflurane, but the recovery times were similar.