Journal of pediatric ophthalmology and strabismus
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J Pediatr Ophthalmol Strabismus · May 1992
Randomized Controlled Trial Comparative Study Clinical TrialA mydriatic eye-drop combination without systemic effects for premature infants: a prospective double-blind study.
Eye drops used for diagnostic mydriasis may produce systemic side effects in preterm infants. Studies on the pupil dilating and systemic effect of various mydriatic agents yielded conflicting results. We conducted a prospective randomized double-blind study on the systemic effect of two mydriatic eye-drop combinations. ⋯ A significant increase of BP and HR peak values was observed within 7 to 10 minutes after the cyclopentolate/tropicamide combination only. On the other hand, the mydriatic effect of the phenylephrine/tropicamide combination was significantly superior to that of the cyclopentolate/tropicamide combination. We recommend the combination of 2.5% phenylephrine and 0.5% tropicamide to achieve a sufficient diagnostic mydriasis without systemic side effects in preterm infants.
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J Pediatr Ophthalmol Strabismus · Mar 1992
Case ReportsA case of developmental glaucoma presenting with abdominal colic and subnormal intraocular pressure.
A healthy baby boy presented with abdominal colic. He was subsequently noted to have enlarged, edematous corneas. A clinical diagnosis of developmental glaucoma was made despite ocular hypotony. ⋯ This served as a biopsy to confirm the diagnosis and as a surgical treatment for the condition. Morphological examination of the outflow system revealed findings compatible with a diagnosis of developmental glaucoma: a hypoplastic trabecular meshwork which contained an abundance of abnormal collagenous tissue in the extracellular spaces and the presence of endothelial cells overlying a continuous collagenous membrane. In the iris stroma there were numerous abnormal blood vessels, with a paucity of mural contractile cells.
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J Pediatr Ophthalmol Strabismus · Sep 1988
True charity and professional life: a patient advocacy program.
The Patient Advocacy Program, built on an already existing, sympathetic hospital staff, has placed added emphasis on the physician-patient relationship which recently has been obscured by increasing technology, mechanization, and third party process. Furthermore, the Patient Advocacy Program stresses that the patient is the most important reason for the focus of the physician and staff. We have tried to exhibit not only true professionalism, but also true charity, by giving more than is expected and in return receiving an appreciative and satisfying response from patients, parents, and responsible parties.
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Cycloplegic drugs are the principal medications used in the diagnosis of accommodative esotropia. The same cycloplegics can be used as a "medical patch" in the treatment of amblyopia. Miotics may be as good as glasses in controlling accommodative esotropia but are almost never better. ⋯ Miotics also may be used as a supplementary agent to glasses, bifocals, or surgery in the treatment of esotropia. The most widely used miotics today include phospholine iodide and DFP with iris cysts being the major local side effect in the eye with the use of miotics in children. Miotics and other drugs are valuable tools in the treatment of accommodative esotropia; however, the use must be correlated with other tools, including surgery, patching, glasses, and orthoptic exercises.