Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Aug 2001
Randomized Controlled Trial Multicenter Study Clinical TrialClinical efficacy of topical docosanol 10% cream for herpes simplex labialis: A multicenter, randomized, placebo-controlled trial.
Recurrent herpes simplex labialis (HSL) occurs in 20% to 40% of the US population. Although the disease is self-limiting in persons with a healthy immune response, patients seek treatment because of the discomfort and visibility of a recurrent lesion. ⋯ Docosanol applied 5 times daily is safe and effective in the treatment of recurrent HSL. Differences in healing time compared favorably with those reported for the only treatment of HSL that has been approved by the Food and Drug Administration.
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J. Am. Acad. Dermatol. · Aug 2001
Review Case ReportsBlack spot poison ivy: A report of 5 cases and a review of the literature.
Black-spot poison ivy dermatitis is a rare manifestation of a common condition. It occurs on exposure to the resins of the plants of the Rhus family also known as Toxicodendron. We describe 5 patients with black deposits on their skin and clothing after contact with poison ivy and review the literature reflecting different aspects of this phenomenon including clinical presentation, histologic findings, and historical background.
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J. Am. Acad. Dermatol. · Jul 2001
Anxiolysis with oral midazolam in pediatric patients undergoing dermatologic surgical procedures.
Pediatric patients undergoing dermatologic surgical procedures often experience high levels of anxiety. Oral midazolam is a short-acting benzodiazepine that can ameliorate procedure-related anxiety. ⋯ Oral midazolam is an effective anxiolytic agent in pediatric patients undergoing dermatologic surgical procedures.
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J. Am. Acad. Dermatol. · Jun 2001
Randomized Controlled Trial Clinical TrialA randomized trial of the Hawaii SunSmart program's impact on outdoor recreation staff.
Skin cancer is the most common form of cancer in the United States and one of the most preventable. Prevention programs for children at outdoor recreation sites may influence not only the youth, but the staff, or caregivers, as well. By teaching children about sun protection, staff may also change their sun protection behaviors. ⋯ Changes in staff behavior and attitudes are important for their own health, as positive role models, and for the dissemination of skin cancer control programs.
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J. Am. Acad. Dermatol. · Jun 2001
Clinical TrialChanges of skin blood flow and color on lesional and control sites during PUVA therapy for psoriasis.
Although the colors of psoriatic lesions, largely determined by erythema and scales, are important clinical indicators, expressing them in an objective manner is difficult. Cutaneous blood flow (CBF) also affects erythema. Serial measurement of these parameters during phototherapy was almost nonexistent. ⋯ Color parameters and CBF were closely related with clinical improvement according to consecutive phototherapy. They may serve as objective indices for the visible morphology and underlying lesional pathophysiology of psoriasis.