Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Jan 1997
Low-dose methotrexate administered weekly is an effective corticosteroid-sparing agent for the treatment of the cutaneous manifestations of dermatomyositis.
The cutaneous manifestations of dermatomyositis can be the most prominent finding and are often difficult to treat. ⋯ Low-dose oral methotrexate administered weekly is effective in treatment of the cutaneous manifestations of dermatomyositis and frequently enables a reduction or discontinuation of corticosteroid therapy.
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J. Am. Acad. Dermatol. · Jan 1997
Comparative StudyA comparative study of three occlusive dressings in the treatment of full-thickness wounds in pigs.
Little objective information is available on the influence of occlusive dressings on the healing of cutaneous full-thickness wounds. ⋯ Wound tissue reactions to different hydrocolloid dressings vary depending on composition. The tissue reactions had no significant effect on wound contraction or epithelialization.
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J. Am. Acad. Dermatol. · Jan 1997
Comparative StudyPostmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris.
Lichen planopilaris usually produces multifocal areas of scarring alopecia. Recently, a condition in postmenopausal women characterized by progressive frontal hairline recession associated with scarring has been described. ⋯ Progressive frontal fibrosing alopecia is a clinically distinct variant of lichen planopilaris that affects in particular elderly women and frequently involves the eyebrows. The basis for this lichenoid tissue reaction targeting frontal scalp follicles and eyebrows is unknown.
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J. Am. Acad. Dermatol. · Dec 1996
ReviewDrug photosensitivity, idiopathic photodermatoses, and sunscreens.
Photosensitization may be defined as a process in which a reaction to normally innocuous radiation is induced by the introduction of a specific radiation-absorbing substance (the photosensitizer) that causes another component (the substrate) to be changed by the radiation. This review focuses on photosensitization produced by exogenous chemicals. ⋯ Clinical recognition patterns of the photodermatoses are stressed as well as several diagnostic procedures available for confirmation of the condition. Finally, descriptions, therapeutic uses, and adverse reactions of sunscreens are provided.
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J. Am. Acad. Dermatol. · Dec 1996
Chronic telogen effluvium: increased scalp hair shedding in middle-aged women.
Diffuse loss of scalp hair is a common problem in middle-aged women. A segment of these cases represents idiopathic chronic telogen effluvium (CTE). ⋯ CTE, which usually affects 30- to 60-year-old women, starts abruptly with or without a recognizable initiating factor. It may be distinguished from classic acute telogen effluvium by its long fluctuating course and from AGA by its clinical and histologic findings.