Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Nov 2005
Case ReportsClomipramine-induced hypersensitivity syndrome with unusual clinical features.
Drug-induced hypersensitivity syndrome is a severe drug eruption with fatal visceral organ failures associated with human herpesvirus-6 (HHV-6) reactivation. We present a case of clomipramine-induced hypersensitivity syndrome, which displayed in succession two different reactions akin to those described for Gianotti-Crosti syndrome and infectious mononucleosis. HHV-6 reactivation was confirmed serologically after the latter reaction, suggesting that our case may have represented a biphasic reaction to HHV-6 reactivation.
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J. Am. Acad. Dermatol. · Oct 2005
Multicenter Study Comparative StudyThe incidence of major complications from Mohs micrographic surgery performed in office-based and hospital-based settings.
There has been significant interest in the safety of office-based surgery. ⋯ Mohs micrographic surgery and repair of associated defects can be safely performed in either an office- or hospital-based setting.
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J. Am. Acad. Dermatol. · Aug 2005
Necrolytic acral erythema: a cutaneous sign of hepatitis C virus infection.
Hepatitis C virus (HCV) infection is globally epidemic. Several mucocutaneous diseases are well established in association with HCV infection. Few case reports describe the recently recognized HCV-related skin disorder termed necrolytic acral erythema (NAE). ⋯ NAE is a distinctive skin disorder associated with HCV infection in all cases reported to date. Recognition of this disease should alert practitioners to the need for viral testing and appropriate counseling of patients.