The Journal of infection
-
The Journal of infection · Feb 2004
Early diagnosis of candidiasis in non-neutropenic critically ill patients.
To determine a method for the early diagnosis of candidiasis in non-neutropenic critically ill patients in order to reduce mortality. ⋯ Invasive candidiasis is related to digestive and respiratory samples and to the presence of non-C. albicans species. A simpler definition of invasive candidiasis in non-neutropenic critically ill patients will permit more rapid and accurate specific antifungal therapy.
-
The Journal of infection · Jan 2004
Fever of unknown origin in Turkey: evaluation of 87 cases during a nine-year-period of study.
To investigate fever of unknown origin (FUO) in 87 patients. ⋯ Infectious diseases, especially tuberculosis, were the leading diagnostic category of FUO in this study. Adult Still's disease was more common than expected. An aetiological diagnosis could not be reached in six (7%) patients who were followed for 1 year. Five of these patients completely recovered, and one patient died.
-
The Journal of infection · Nov 2003
Clinical prognostic markers in patients with severe sepsis: a prospective analysis of 139 consecutive cases.
To analyze the clinical characteristics and determine predictive factors of mortality in previously healthy individuals suffering from severe sepsis. ⋯ Septic patients with advanced age, septic shock, renal failure, DIC and metabolic acidosis on admission are at increased risk of mortality. The sustained presence of high SAPS-II and lactacidemia one week after admission are also important risk factors of poor outcome.
-
The Journal of infection · Nov 2003
Are infections due to resistant pathogens associated with a worse outcome in critically ill patients?
To evaluate the outcome of critically ill patients infected with antimicrobial resistant microorganisms, and to analyse the factors involved in the development of antimicrobial resistance. ⋯ Infection with antimicrobial resistant microorganisms is not an independent predictor for death. The development of antimicrobial resistance is related to the previous use of multiple antibiotics, the ICU length of stay, and the severity of hepatic dysfunction.
-
The Journal of infection · Nov 2003
Case ReportsIleitis due to Yersinia pseudotuberculosis in Crohn's disease.
We present the case of a young woman with fulminating terminal ileitis due to Yersinia pseudotuberculosis, in whom Crohn's disease was subsequently diagnosed. Serological testing was prompted by radiological, macroscopic and histological changes which were atypical of Crohn's disease. ⋯ In this case, the classical features of Y. pseudotuberculosis may have been modified by pre-existing Crohn's disease. We propose that, because of defects in mucosal barrier function and immunological function, patients with Crohn's may have increased susceptibility to infection by Yersinia sp.