The Journal of infection
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The Journal of infection · Jul 2002
Letter Case ReportsCitrobacter koseri pneumonia and meningitis in an infant.
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The Journal of infection · May 2002
Impact of respiratory syncytial virus infection as a cause of lower respiratory tract infection in children younger than 3 years of age in Japan.
Respiratory syncytial virus (RSV) is the most important viral pathogen for lower respiratory tract infection (LRI) in infants and children. An RSV-specific monoclonal antibody has been developed to provide prophylaxis against RSV associated LRI (RSV-LRI). The objective of this study was to determine the impact of RSV as a cause of LRI in children younger than 3 years of age to provide data to aide in the implementation of forthcoming prophylaxis against RSV. ⋯ The incidence of LRI hospitalization is highly affected by RSV infection epidemic. The proportion of RSV infections among early infants younger than 6 months is greater than that of older patients. The prophylaxis against RSV will be needed to be toward early infants.
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The Journal of infection · Apr 2002
Case ReportsCandida parapsilosis: two cases of endocarditis in association with the Toronto stentless porcine valve.
Candida parapsilosis endocarditis in association with prosthetic heart valves is rare. We report the first two cases of C. parapsilosis endocarditis on the Toronto stentless porcine valve (TSPV) and the first reported case of successful elimination of infection without lifelong antifungal therapy.
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Meningococcal disease is the leading infective cause of mortality in children. Bronchiolitis and meningococcal disease share some common features. ⋯ We report two cases of meningococcal disease in infants whose initial presentation was suggestive of bronchiolitis. We draw attention to tachypnoea as an important but overlooked early sign of meningococcal septicaemia.
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The Journal of infection · Nov 2001
The causes of fever in children attending hospital in the north of England.
Fever is a common symptom in children presenting to casualty. Identifying the seriously ill is difficult. Previous studies, mainly from North America, suggest that symptoms, signs and simple investigations may help to do this. The aim of the present study was to assess the causes of fever and identify clinical and laboratory features suggesting serious disease in U.K. children presenting to hospital with temperatures >or=38 degrees C. ⋯ One out of three of children referred with fever had a serious disease. Degree of temperature and WBC count were poor predictors of serious disease. Interestingly, poor feeding and restlessness were more sensitive predictors, suggesting high fever and WBC count can not replace clinical assessment of the child with a temperature.