Journal of periodontology
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Journal of periodontology · Sep 2011
Randomized Controlled Trial Comparative StudyThe use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial.
Postoperative pain is an adverse effect of periodontal surgeries and may therefore be prevented or minimized. This study was conducted to evaluate the clinical efficacy of two selective cyclooxygenase-2 inhibitors, celecoxib and etoricoxib, on pain prevention after periodontal surgery. ⋯ It was concluded that a single etoricoxib dose is not superior to two split doses of celecoxib when used for pain prevention after open-flap debridement surgery.
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Journal of periodontology · Jul 2011
Randomized Controlled Trial Comparative StudyEvaluation of novel adhesive film containing ketorolac for post-surgery pain control: a safety and efficacy study.
Prescribing analgesics after periodontal surgery is a common practice. However, it can become a challenge for patients with systemic diseases or who are on long-term medications. Ketorolac tromethamine (KT), a non-steroidal anti-inflammatory drug, is incorporated into an adhesive film to overcome the limitations associated with oral, intravenous, intramuscular, or sublingual routes of drug administration. This study evaluates the analgesic effect of a KT adhesive film for pain management after periodontal surgery. ⋯ Adhesive film containing 30 mg of KT was effective in controlling post-surgical pain with no observable gastrointestinal effects.
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Journal of periodontology · Jun 2011
Outcomes in patients visiting hospital emergency departments in the United States because of periodontal conditions.
The chances of presenting to hospital emergency departments (EDs) are significantly higher in individuals who ignore regular dental care and in those with medical conditions. Little is known about nationwide estimates of hospital-based ED visits caused by periodontal conditions in the United States. The objective of this study is to determine the incidence of ED visits caused by periodontal conditions that occurred in a 2006 nationwide sample and to identify the risk factors for hospitalization during the ED visits. ⋯ Estimates from the NEDS suggest that a total of 85,039 hospital-based ED visits had a primary diagnosis for periodontal conditions. Close to $33.3 million was charged by hospitals for treating these conditions on an emergency basis. ED visits with a primary diagnosis for acute and aggressive periodontitis, covered by Medicare insurance, and comorbid conditions were more likely to result in hospitalization based on the analysis of the NEDS. However, when interpreting these conclusions, one should keep the limitations inherent to hospital discharge datasets in perspective.
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Journal of periodontology · May 2011
Comparative StudyAcute myocardial infarction is reflected in salivary matrix metalloproteinase-8 activation level.
The aim of this study is to compare salivary and serum biomarker levels and degrees of matrix metalloproteinase (MMP) activation between patients with acute myocardial infarction (AMI) and systemically healthy patients (non-AMI) with similar periodontal conditions. ⋯ Total salivary MMP-8 assessed by immunofluorometric assay method and immunoblot densitometric units was higher in non-AMI than in AMI patients' saliva, but a significantly higher percentage of AMI patients' MMP-8 was activated polymorphonuclear leukocyte (PMN) type (P <0.001) regardless of periodontal diagnosis.Serum MMP-8, MMP-9, and TIMP-1 levels were significantly higher in AMI (for all markers and all comparisons,P <0.05). Characteristic for AMI was dominance of active PMN MMP-8 in saliva [corrected].
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Journal of periodontology · Feb 2011
Randomized Controlled TrialEffect of eutectic mixture of local anesthetics on pain perception during scaling by ultrasonic or hand instruments: a masked randomized controlled trial.
The aims of this study are to evaluate the efficacy of a eutectic mixture of local anesthetic (EMLA) cream on pain perception during scaling and to compare the intensities of pain provoked by hand and ultrasonic instruments. ⋯ Although most patients experienced limited pain during scaling, a significant reduction of pain is achieved by using EMLA cream and ultrasonic scaler.