Annals of emergency medicine
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Randomized Controlled Trial
Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial.
We hypothesized that the use of intramuscular ketamine would result in a clinically relevant shorter time to target sedation. ⋯ In ED patients with severe agitation, intramuscular ketamine provided significantly shorter time to adequate sedation than a combination of intramuscular midazolam and haloperidol.
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We retrospectively evaluated the implementation of low-threshold emergency department (ED) buprenorphine treatment at 52 hospitals participating in the CA Bridge Program using the RE-AIM (reach, effectiveness, adoption, implementation, maintenance) framework. ⋯ Low-threshold ED buprenorphine treatment implemented with a harm reduction approach and active navigation to outpatient addiction treatment was successful in achieving buprenorphine treatment for opioid use disorder in diverse California communities.