AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Jan 2008
CT perfusion-derived mean transit time predicts early mortality and delayed vasospasm after experimental subarachnoid hemorrhage.
There are limited indicators available to predict cerebral vasospasm in patients with subarachnoid hemorrhage (SAH). The purpose of this study was to determine if CT perfusion-derived hemodynamic parameters are predictors of vasospasm severity and outcome after experimental SAH. ⋯ In the rabbit model of experimental SAH, the CT-derived hemodynamic parameter MTT on day 0 predicted early mortality, and MTT on day 2 predicted development of moderate-severe delayed vasospasm. MTT was also significantly correlated with arterial diameter and neurologic score.