AJNR. American journal of neuroradiology
-
AJNR Am J Neuroradiol · May 2003
Case ReportsDemonstration of an actively bleeding aneurysm by CT angiography.
We describe a case of an actively bleeding aneurysm demonstrated by CT angiography (CTA). The active hemorrhage was characterized by a nebulous attenuation in the subarachnoid space adjacent to the aneurysm. The measurements (HU) of the hemorrhage were equal to or slightly less than those of the contrast material in the arteries and diminished as one moved further from the aneurysm. As CTA is used more frequently in the diagnosis of cerebral aneurysms, it is important to understand imaging features of this potentially lethal condition.
-
AJNR Am J Neuroradiol · Apr 2003
Diffusion-tensor imaging for the detection and quantification of treatment-induced white matter injury in children with medulloblastoma: a pilot study.
Treatment-induced white matter (WM) injury in medulloblastoma survivors, as manifested by deterioration of cognitive function, is prevalent. However, no reliable imaging method exists for early detection and quantification. Our goal was to determine whether anisotropy of WM is reduced in medulloblastoma survivors and whether fractional anisotropy (FA) can be used as an index for evaluation of treatment-induced WM injury. ⋯ DT imaging and use of the index FA is potentially useful for early detection and monitoring of treatment-induced WM injury in children with medulloblastoma.
-
AJNR Am J Neuroradiol · Apr 2003
Aneurysmal subarachnoid hemorrhage in patients with Hunt and Hess grade 4 or 5: treatment using the Guglielmi detachable coil system.
Patients in poor clinical condition (Hunt and Hess grade 4 or 5) after subarachnoid hemorrhage (SAH) have historically fared poorly and many often were excluded from aggressive treatment. Early aggressive surgical treatment of SAH can produce good-quality survival for a higher percentage of patients than previously reported. We assessed the outcome of patients with Hunt and Hess grade 4 or 5 who were treated with Guglielmi detachable coil (GDC) embolization. ⋯ Patients with Hunt and Hess grade 4 or 5 after SAH can undergo successful coil embolization of the aneurysms despite their poor medical condition and a high frequency of vasospasm at the time of treatment. Morbidity and mortality rates with this disease are still high. These findings compare favorably with those published in surgical series for aggressively treated patients with Hunt and Hess grade 4 or 5.
-
AJNR Am J Neuroradiol · Apr 2003
MR imaging enhancement patterns as predictors of hemorrhagic transformation in acute ischemic stroke.
Early parenchymal gadolinium enhancement on T1-weighted MR images is predictive of hemorrhagic transformation (HT) in rodent focal ischemia models, but its value in humans is unknown. We sought to investigate gadolinium enhancement in acute ischemic stroke patients to determine their association with subsequent HT. ⋯ Early parenchymal enhancement of stroke lesions may be a good predictor of subsequent symptomatic HT may help identify patients at risk, especially after thrombolytic therapy.
-
AJNR Am J Neuroradiol · Apr 2003
MR imaging volumetry of subcortical structures and cerebellar hemispheres in normal persons.
Volume changes in subcortical structures and cerebella have been associated with localization-related epilepsy and psychiatric illnesses. This study evaluated the effect of handedness and sex on the volumes of selected subcortical structures and cerebellar hemispheres in normal persons. ⋯ These findings show that women have significantly larger subcortical structures than do men after spatial normalization to account for differences in brain size. Sex-specific normal ranges may be needed for evaluating volume changes related to epilepsy or other disease processes.