AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Apr 1996
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
To test clinical proton MR spectroscopy as a noninvasive method for predicting tumor malignancy. ⋯ Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values. These results suggest that clinical proton MR spectroscopy may help predict tumor malignancy.
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AJNR Am J Neuroradiol · Mar 1996
The forgotten condyle: the appearance, morphology, and classification of occipital condyle fractures.
To evaluate the appearance, morphology, and treatment of occipital condyle fractures (OCF). ⋯ Although OCFs are rare, they will be encountered by most radiologists who see a significant amount of trauma. Type II OCFs were the most common fracture type in our series. Type III fractures were the second most common and potentially unstable. CT should be initiated at the level of the C-1 ring to screen for the presence of OCF in all patients who have suffered trauma.
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AJNR Am J Neuroradiol · Feb 1996
Case ReportsTraumatic aneurysm of the internal carotid artery: a late finding presenting as a mass in the sphenoid sinus.
We describe a case of a traumatic aneurysm of the cavernous portion of the internal carotid artery in a patient who had had craniofacial trauma 12 years before. MR and CT revealed a mass in the sphenoid sinus thought to be unrelated to the patient's symptoms. Carotid angiography gave the correct diagnosis.
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AJNR Am J Neuroradiol · Feb 1996
Neurotoxic effects of gadopentetate dimeglumine: behavioral disturbance and morphology after intracerebroventricular injection in rats.
To determine the neurotoxic potential of gadopentetate dimeglumine in an animal model that allowed the agent to avoid the blood-brain barrier. Gadopentetate dimeglumine is known to produce functional changes when injected into the cerebrospinal fluid, and we hypothesized that such changes might be associated with morphologic damage. ⋯ Intraventricular administration of contrast medium allows toxicity to be evaluated in areas such as the spinal cord that are not accessible by osmotic opening. While it is unlikely that these toxic effects would be seen at the doses used for clinical imaging by the intravenous route, gadopentetate dimeglumine clearly has some neurotoxic and neuropathologic potential. Although the acute excitation could be attributed to a transiently high local concentration of the agent at the injection site, the lesions were widely distributed through the brain and spinal cord and may reflect a region-specific neurotoxic action, possibly related to central pontine myelinolysis.
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Three cases of cerebral lymphoma in patients with acquired immunodeficiency syndrome is presented. They are remarkable for their extremely rapid progression, which simulated an infectious processes during trials of antitoxoplasma therapy. Fourteen days of therapy are generally required to assess a negative response. However, earlier biopsies and shorter therapeutic trials may be indicated in these patients.