European heart journal
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European heart journal · Apr 1997
ReviewEffects of beta-blocker therapy on mortality in patients with heart failure. A systematic overview of randomized controlled trials.
Several randomized trials have reported that beta-blocker therapy improves left ventricular function and reduces the rate of hospitalization in patients with congestive heart failure. However, most trials were individually too small to assess reliably the effects of treatment on mortality. In these circumstances a systematic overview of all trials of beta-blocker therapy in patients with congestive heart failure may provide the most reliable guide to treatment effects. ⋯ Beta-blocker therapy is likely to reduce mortality in patients with heart failure. However, large-scale, long-term randomized trials are still required to confirm and quantify more precisely the benefit suggested by this overview.
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European heart journal · Apr 1997
Social class and coronary disease in rural population of north India. The Indian Social Class and Heart Survey.
To demonstrate the association of socio-economic status with prevalence of coronary artery disease and coronary risk factors. ⋯ Subjects in social classes 1 and 2 in rural North India have a higher prevalence of coronary artery disease and of the coronary risk factors hypercholesterolaemia, hypertension, higher body mass index and sedentary lifestyle. The overall prevalence of coronary artery disease was 3.3%.
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European heart journal · Mar 1997
ReviewBody habitus and coronary heart disease in men. A review with reference to methods of body habitus assessment.
Table 1 is a synopsis of the major findings from an extensive literature on the association between human body habitus and coronary heart disease. Whilst some studies have used quite sophisticated laboratory procedures to quantify body fat most have relied upon anthropometric measurements to determine some component of body habitus. Of these, body weight and height are the simplest measurements and are, therefore, well-suited to large-scale prospective studies. ⋯ When follow-up periods exceed 20 years, and sample size is small, however, this closer association has not been found, even with a long follow-up period. Whilst some studies have found no association after 15, 13 and 12 years others have reported a relationship after 8.5, 10, 12, 10 and 7 years. The 22 year follow-up evidence from the Framingham Study shows the strongest 'independent' association between body mass index and coronary heart disease. (ABSTRACT TRUNCATED)
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European heart journal · Feb 1997
Editorial CommentFuture of paediatric cardiology and its patients.