La Revue de médecine interne
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Case Reports
[Thrombotic thrombocytopenic purpura and ankylosing spondylarthritis. Apropos of a case].
The authors report a case of thrombotic thrombocytopenic purpura (TTP) which revealed a hitherto unrecognized ankylosing spondylitis. After a 4-year follow-up, the spondylitis is still progressing in its axial and/or peripheral form, and TTP has not relapsed. ⋯ The TTP-ankylosing spondylitis association is extremely rare: analysis of the literature yielded only one case. The authors discuss the hypothesis of a common triggering factor.
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The authors report retrospectively 38 cases of Schönlein-Henoch purpura (20 males, 18 females; median age, 26 years). Skin (37/38) and joint (21/38) manifestations are similar to those seen in children. Gastro intestinal (22/38) manifestations are less complicated. Long term outcome of the disease depends on kidney's involvement (32/38) and is severe: chronic renal failure in 31%.
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Case Reports
[Spontaneous dissection of the anterior interventricular coronary artery in the postpartum period].
We report a case of anterior myocardial infarction which occurred in a young woman without history of cardio-vascular disease 10 days after she had given birth. Coronary arteriography performed 2 months later showed a pseudo-aneurysm of the anterior interventricular artery consecutive to spontaneous dissection of this vessel. The other coronary arteries were normal.
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We report four cases of multiple arterial dissection associated with an inflammatory syndrome. The features of lesions and the absence of histological inflammatory arterial disease suggest an arterial dysplasia complicated by an infectious disease.
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Review Case Reports
[Lambert-Eaton syndrome and small cell cancer. Etiopathogenic considerations apropos of 2 cases].
The authors report two cases of Lambert-Eaton myasthenic syndrome associated with small cell lung carcinoma. Following the observations, the clinical diagnosis of this syndrome is considered. ⋯ Small cell carcinoma cells appear to express calcium channels, suggesting that autoantibody production may be triggered by tumor calcium channels determinants. The autoimmune paraneoplastic syndrome theory refers to cross-antigenicity.