Fortschritte der Neurologie-Psychiatrie
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Fortschr Neurol Psychiatr · Nov 2006
Biography Historical Article[Homage to Kraepelin, honouring his 150th birthday--"Zerfahrenheit", Kraepelin's specific symptom for schizophrenia].
Kraepelin described but one single specific sign for all forms of dementia praecox (later: schizophrenia) and coined a new word for it, "Zerfahrenheit" (various translations: distraction, dilapidation, incoherence, among others). What he meant by it, clearly results from Kraepelin's description even now. The origin of the idea could been found in German philosophy of the times of enlightenment, when it had been described already in a distinct way. ⋯ No corrections or changes are necessary. Kraepelin's 150th birthday is the best occasion for reminding of what remains unique in the clinical unity of schizophrenia, which for ever is linked to his name. It still is a solid sign for schizophrenia, for all its various forms.
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Fortschr Neurol Psychiatr · Nov 2006
[Management of incidental findings in neuroimaging in diagnosis and pathophysiological research].
Structural, quantitative and functional neuroimaging has contributed greatly to the advancement in clinical diagnosis and research into pathophysiology of psychiatric disorders. In diagnostic investigations, the frequency of "incidental" findings, i. e. potentially pathological findings, which are unexpected with regards to the primary diagnostic question and which cannot be related to the presenting clinical symptomatology, amounts up to 30 %. ⋯ Several medical, ethical and legal problems arise related to the detection, evaluation and documentation of incidental findings in clinical experimental studies. These problems and resulting obligations will be discussed and solutions with respect to the management of incident findings will be proposed.