Pharmacotherapy
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Comparative Study Clinical Trial
Daptomycin versus vancomycin for complicated skin and skin structure infections: clinical and economic outcomes.
To assess the effect of daptomycin compared with vancomycin on the clinical and economic outcomes in patients with complicated skin and skin structure infections. ⋯ Patients receiving daptomycin achieved more rapid resolution of symptoms and clinical cure and had a decreased duration of inpatient therapy compared with those receiving vancomycin. This study suggests that daptomycin is a cost-effective alternative to vancomycin for complicated skin and skin structure infections.