Cephalalgia : an international journal of headache
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Data on clinical differences between episodic (eCH) and chronic cluster headache (cCH) and accompanying migraine features are limited. ⋯ Occurrence of CAS and attack frequency, as well as periodic patterns of attacks, are relatively uniform in eCH and cCH. Multiple CAS are not related to pain intensity. Allodynia during cluster attacks is a frequent symptom. The unexpectedly high rate of accompanying migrainous features during cluster attacks cannot be explained by comorbid migraine.
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Osmophobia is frequent in children with migraine (20-35%) but can also occur in up to 14% of cases with tension-type headache (TTH). So far, the prognostic role of this symptom in children with primary headaches has never been evaluated. ⋯ Our data confirm that osmophobia has an important diagnostic and prognostic role in children with primary headaches and should be systematically investigated at diagnosis and during follow-up.
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Randomized Controlled Trial
Botulinum toxin type A for the treatment of trigeminal neuralgia: results from a randomized, double-blind, placebo-controlled trial.
To investigate the efficacy, safety and tolerability of intradermal and/or submucosal administration of botulinum toxin type A (BTX-A) for patients with trigeminal neuralgia (TN). ⋯ BTX-A may be an efficient, safe and novel strategy for TN treatment.
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Few clinic-based studies report an association between migraine and restless legs syndrome (RLS); however, population-based data are unavailable. ⋯ Our data suggest an association between migraine and RLS at the population level. The association is similar for migraine with and without aura and for new reports of migraine during follow-up.
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To estimate the 1-year prevalences of primary headache disorders and identify their principal risk factors in the general population of Russia. ⋯ The study demonstrated a high prevalence of migraine and a very high prevalence of headache on ≥15 days/month, and revealed unmet health-care needs of people with headache in Russia.