Journal of cellular biochemistry
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Retraction: "Protective impacts of long noncoding RNA taurine-upregulated 1 against lipopolysaccharide-evoked injury in MRC-5 cells through inhibition of microRNA-127," by Jie Meng, Yan Chen, Cunxue Zhang, J Cell Biochem. 2019; 14928-14935: The above article, published online on 24 April 2019 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/10.1002/jcb.28755), has been retracted by agreement between the the journal's Editor in Chief, Prof. Dr. ⋯ Several flaws and inconsistencies between results presented and experimental methods described were found, the editors consider the conclusions of this article to be invalid. The authors collaborated in the investigation initially, but were not available for a final confirmation of the retraction.
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Retraction: "Silence of cZNF292 suppresses the growth, migration, and invasion of human esophageal cancer Eca-109 cells via upregulating miR-206," by Zengjia Liu, Guiju Hu, Yan Zhao, Zuorun Xiao, Mingzhe Yan, Mei Ren, J Cell Biochem. 2020; 2354-2362: The above article, published online on 03 November 2019 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.29458), has been retracted by agreement between the the journal's Editor in Chief, Prof. Dr. ⋯ Several flaws and inconsistencies between results presented and experimental methods described were found, the editors consider the conclusions of this article to be invalid. The authors collaborated in the investigation initially, but were not available for a final confirmation of the retraction.
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Retraction: "Upregulation of long noncoding RNA TUG1 contributes to the development of laryngocarcinoma by targeting miR-145-5p/ROCK1 axis," by Shenfa Zhuang, Fengxian Liu, Pingping Wu, J Cell Biochem. 2019; 13392-13402: The above article, published online on 27 March 2019 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.28614), has been retracted by agreement between the the journal's Editor in Chief, Prof. Dr. ⋯ Several flaws and inconsistencies between results presented and experimental methods described were found, the editors consider the conclusions of this article to be invalid. The authors collaborated in the investigation initially, but were not available for a final confirmation of the retraction.
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The coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains an extant threat against public health on a global scale. Cell infection begins when the spike protein of SARS-CoV-2 binds with the human cell receptor, angiotensin-converting enzyme 2 (ACE2). Here, we address the role of tetracycline as an inhibitor for the receptor-binding domain (RBD) of the spike protein. ⋯ Tetracycline binds to tyrosine and glycine residues on the viral contact interface that are known to modulate molecular recognition and bonding affinity. These RBD residues also engage in significant hydrogen bonding with the human receptor ACE2. The ability to preclude cell infection complements the anti-inflammatory and cytokine suppressing capability of tetracycline; this may reduce the duration of ICU stays and mechanical ventilation induced by the coronavirus SARS-CoV-2.
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"Long noncoding RNA SNHG14 contributes to gastric cancer development through targeting miR-145/SOX9 axis," by Zhao Liu, Yan Yan, Sizhe Cao, Yi Chen, J Cell Biochem. 2018; 6905-6913: The above article, published online on 18 April 2018 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1002/jcb.26889), has been retracted by agreement between the authors, the journal's Editor-in-Chief, Prof. Dr. ⋯ Raw data could not be provided and thus the validity of the overall results could not be confirmed. The authors also admit several flaws in the presented Transwell Assays.