Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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J. Oral Maxillofac. Surg. · Oct 1999
Randomized Controlled Trial Comparative Study Clinical TrialThe effect of preoperative ondansetron on the incidence of postoperative nausea and vomiting in patients undergoing outpatient dentoalveolar surgery and general anesthesia.
The purpose of this investigation was to evaluate the efficacy of ondansetron in controlling postoperative nausea and vomiting (PONV) when used prophylactically in patients undergoing routine dentoalveolar surgery performed under general anesthesia. ⋯ Based on the results of this study, PONV occurred in approximately 20% of patients (20% for nausea, 8% for vomiting). With the types of anesthetic agents and techniques used in this investigation, there were no significant differences between ondansetron and placebo for prophylaxis against PONV.
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J. Oral Maxillofac. Surg. · Jun 1999
Factors influencing condylar position after the bilateral sagittal split osteotomy fixed with bicortical screws.
Multiple articles have discussed condylar position after bilateral sagittal split osteotomy (BSSO). However, previous studies have been limited to two-dimensional evaluation of condylar position. The purpose of this study was to evaluate change in condylar position after a BSSO fixed with bicortical screws using three-dimensional computed tomography to assess the factors that may influence the ultimate position of the condyle after surgery. ⋯ There are obvious changes in condyle position after a BSSO. These changes appear to be influenced mainly by factors other than amount of advancement, degree of proximal segment rotation, and shape of the mandible.
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J. Oral Maxillofac. Surg. · Jun 1999
Additive analgesic effects of oxycodone and ibuprofen in the oral surgery model.
A traditional approach to achieve greater analgesic efficacy is to combine an efficacious dose of a nonopioid with a dose of an opioid sufficient to produce additive analgesia without a substantial increase in the incidence of adverse effects. This study evaluated the additive analagesic effects of the combination of ibuprofen and oxycodone. ⋯ These results indicate that additive analgesia can be achieved for the combination of a nonsteroidal anti-inflammatory drug and an orally effective opioid, with faster onset of relief for the combination of 400 mg ibuprofen and 10 mg oxycodone over the first 2 hours after administration, but at the expense of an increased incidence of adverse events.