Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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J. Oral Maxillofac. Surg. · Mar 2015
Randomized Controlled Trial Comparative StudyA prospective, randomized controlled trial of conscious sedation using propofol combined with inhaled nitrous oxide for dental treatment.
Adverse reactions during propofol sedation include a decrease in arterial blood pressure, propofol-induced pain on injection, and airway complications. The purpose of this study was to investigate whether combined use of intravenous propofol and inhaled nitrous oxide could decrease the hypotensive and other adverse effects of propofol. ⋯ The results of this study suggest that nitrous oxide inhalation combined with propofol sedation attenuates the hypotensive effect and pain associated with propofol injections, along with potentiating the amnesic effect.
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J. Oral Maxillofac. Surg. · Feb 2015
Randomized Controlled TrialA prospective randomized controlled trial of two different sedation sequences for third molar removal in adults.
In oral and maxillofacial outpatient surgery, sedation techniques are an important component in patient management for a wide variety of surgical procedures. Fentanyl and midazolam are commonly used sedatives with different mechanisms of action and specific analgesic or amnestic properties. This study examined whether the order of their administration would affect a patient's pain perception or procedural vital signs. ⋯ In this study, selective sequencing of midazolam or fentanyl during an intravenous moderate-sedation procedure did not result in a measurable difference of recollected procedural pain scores at 24 hours after third molar extraction. The choice of the sedation agents and the order of their administration should be tailored to the patient's needs, type of surgical procedure, and surgeon preference.
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J. Oral Maxillofac. Surg. · Feb 2015
Multimodal protocol reduces postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy.
To assess the impact of a multimodal antiemetic protocol on postoperative nausea and vomiting (PONV) after Le Fort I osteotomy. ⋯ This multimodal protocol was associated with substantially decreased prevalence of PONV in patients undergoing Le Fort I osteotomy.
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J. Oral Maxillofac. Surg. · Jan 2015
Randomized Controlled Trial Comparative StudyEffect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial.
Perioperative hemorrhage is an important concern during orthognathic surgery. The purpose of this study was to assess the effect of tranexamic acid (TXA) irrigation on perioperative hemorrhage during orthognathic surgery. ⋯ TXA is effective in reducing intraoperative blood loss in patients for whom substantial blood loss is anticipated.