Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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J. Oral Maxillofac. Surg. · Oct 2008
A bioabsorbable collagen nerve cuff (NeuraGen) for repair of lingual and inferior alveolar nerve injuries: a case series.
This study describes the results of using NeuraGen (Integra LifeSciences, Plainsboro, NJ) as a nerve cuff for repair of lingual and inferior alveolar nerve injuries following third molar surgery. ⋯ While reports of the use of other alloplastic materials for nerve repair were found to be variable, NeuraGen seems to have good preliminary results. Bioresorption is complete which decreases the likelihood of interneural scarring. Also, NeuraGen is not associated with episodes of compression neuropathy reported with other rigid non biodegradable materials. Its use in hand surgery literature and in experimental animal studies showed no statistical significance in outcome when compared to end-to-end anastomosis or nerve grafts. The reported advantage of NeuraGen was the elimination of problems associated with graft harvesting. In this small series, 8 out of 9 nerve repairs showed sensory improvement which suggests a favorable role of NeuraGen as a nerve cuff and protective barrier around the nerve injury site. While primary end-to-end anastomosis has comparable results, a nerve cuff has the advantage of preventing axonal escape at suture lines, it minimizes scar ingrowth and nerve entrapment, and it concentrates growth factors at the injury site.
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J. Oral Maxillofac. Surg. · Sep 2008
Comparative StudyChanges in partial pressure of arterial carbon dioxide induces redistribution of oral tissue blood flow in the rabbit.
The purpose of this study was to investigate the effect of changes in partial pressure of arterial CO(2) (PaCO(2)) on oral tissue blood flow. ⋯ Changes in PaCO(2) may induce a redistribution of oral tissue blood flow during both ISO and PROP anesthesia.
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J. Oral Maxillofac. Surg. · Aug 2008
Randomized Controlled Trial Comparative StudyEffect of botulinum toxin-A in myofascial pain patients with or without functional disc displacement.
To evaluate the effects of botulinum toxin-A in the treatment of patients who have myofascial pain with or without functional disc displacement. ⋯ The injection of botulinum toxin-A decreases the muscle action potential in 14 days. The patients also show improvement in pain and psychological status.