Nefrología : publicación oficial de la Sociedad Española Nefrologia
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Low y serum albumin and high C-reactive protein (CRP) have been shown to be significant predictors of mortality in hemodialysis (HD) patients. Although hypoalbuminemia has been attributed to malnutrition, it has recently been recognized evidence of inflammation that predicts serum albumin concentration in dialysis patients. ⋯ Malnutrition is a common problem in HD patients. Low dialysis dose is associated with malnutrition in some patients. We propose to normalize urea clearances to ideal body weight. Inflammatory activity is frequent in HD, probably as a result of intermittent activation of the acute phase response during the dialysis procedure. Low serum albumin in HD patients is principally associated with infection/inflammation but not with malnutrition. CRP is a sensitive marker of inflammation and an power predictor of mortality in HD patients.
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Comparative Study
[Hormonal profile and participation of nitric oxide in salt-sensitive and salt-resistant essential arterial hypertension].
Recent studies have shown that cardiovascular events and end-organ damage occur more frequently in patients with salt-sensitive essential hypertension (SH) than in salt-resistant essential hypertension (RH). Nitric oxide (NO) plays an important role in regulating the pressure-natriuresis relationship. Therefore impaired NO synthesis may produce or aggravate salt-sensitive hypertension. ⋯ During high sodium intake SS patients became non-dippers. Our results showed that patients with salt sensitive hypertension displayed a suppressed renin-aldosterone system, an attenuated nocturnal decline in blood pressure on high-salt diet and an impairment of endothelial function. The relationship between urinary nitrate excretion and arterial pressure suggest that the salt sensitivity of arterial pressure may be related bo blunted generation of endogenous nitric oxide.
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The accuracy of the reference list is considered an essential factor in determining the quality of a scientific publication, and has been reviewed and published in several medical journals. The rate of citation errors in NEFROLOGIA has not been published before. The aim of this study has been to examine the accuracy of the references citation in the numbers of the journal published for a period of 15 years, from the first issue in 1981 to the last one on 1995. ⋯ The issues of NEFROLOGIA published in this period present a high number of bibliographic reference errors, being the rate similar to other evaluated scientific periodical journals. This fact should be improved, and authors and reviewers should thoroughly check their references in order to avoid these mistakes, as they affect the quality standard of the publication.