Journal of the American College of Cardiology
-
J. Am. Coll. Cardiol. · Feb 2007
Randomized Controlled Trial Comparative StudyUltrafiltration versus intravenous diuretics for patients hospitalized for acute decompensated heart failure.
This study was designed to compare the safety and efficacy of veno-venous ultrafiltration and standard intravenous diuretic therapy for hypervolemic heart failure (HF) patients. ⋯ In decompensated HF, ultrafiltration safely produces greater weight and fluid loss than intravenous diuretics, reduces 90-day resource utilization for HF, and is an effective alternative therapy. (The UNLOAD trial; http://clinicaltrials.gov/ct/show/NCT00124137?order=1; NCT00124137).
-
J. Am. Coll. Cardiol. · Feb 2007
Total liquid ventilation provides ultra-fast cardioprotective cooling.
We tested whether total liquid ventilation (TLV) can be used to rapidly cool and protect the infarcting heart. ⋯ Total liquid ventilation can elicit rapid cardioprotective cooling during ischemia.
-
J. Am. Coll. Cardiol. · Feb 2007
Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation.
This study sought to identify whether obesity and obstructive sleep apnea (OSA) independently predict incident atrial fibrillation/flutter (AF). ⋯ Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.