Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Sep 2011
Review Meta AnalysisEffects of beta-adrenergic antagonists in patients with chronic kidney disease: a systematic review and meta-analysis.
The aim of this systematic review was to study the benefits and risks of beta-adrenergic antagonists (beta-blockers) in patients with chronic kidney disease (CKD). ⋯ Treatment with beta-blockers improved all-cause mortality in patients with CKD and chronic systolic heart failure. There is insufficient evidence to conclude whether people with CKD who are not known to have heart failure derive benefit from beta-blockers.