Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Apr 2014
Multicenter StudyHow does the ascending aorta geometry change when it dissects?
The purpose of this study is to delineate changes in aortic geometry and diameter due to dissection. ⋯ Geometry of the thoracic aorta is affected by aortic dissection, leading to an increase in diameter that is most pronounced in the ascending aorta. Both spontaneous and retrograde dissection result in similar aortic geometry changes.
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J. Am. Coll. Cardiol. · Apr 2014
Multicenter Study Comparative Study Clinical TrialMulticenter core laboratory comparison of the instantaneous wave-free ratio and resting Pd/Pa with fractional flow reserve: the RESOLVE study.
This study sought to examine the diagnostic accuracy of the instantaneous wave-free ratio (iFR) and resting distal coronary artery pressure/aortic pressure (Pd/Pa) with respect to hyperemic fractional flow reserve (FFR) in a core laboratory-based multicenter collaborative study. ⋯ This comprehensive core laboratory analysis comparing iFR and Pd/Pa with FFR demonstrated an overall accuracy of ~80% for both nonhyperemic indices, which can be improved to ≥90% in a subset of lesions. Clinical outcome studies are required to determine whether the use of iFR or Pd/Pa might obviate the need for hyperemia in selected patients.