Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Mar 2010
Clinical TrialEffect of cyclosporine on left ventricular remodeling after reperfused myocardial infarction.
This study examined the effect of a single dose of cyclosporine administered at the time of reperfusion on left ventricular (LV) remodeling and function by cardiac magnetic resonance 5 days and 6 months after myocardial infarction. ⋯ Cyclosporine used at the moment of acute myocardial infarction reperfusion persistently reduces infarct size and does not have a detrimental effect on LV remodeling. These results are preliminary and must be supported by further studies. (Ciclosporin A and Acute Myocardial Infarction; NCT00403728).
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J. Am. Coll. Cardiol. · Mar 2010
Comparative StudyReport of a National Heart, Lung, And Blood Institute Workshop: heterogeneity in cardiometabolic risk in Asian Americans In the U.S. Opportunities for research.
The Asian and Pacific Islander population (Asian Americans) in the U. S. has increased dramatically in the last few decades. Yet, data on cardiovascular disease (CVD) in this population are scarce. ⋯ S. lifestyles affects health and CVD risk among relatively homogenous groups of recent immigrants. Given the heterogeneity in body weight, body size, and CVD risk, the Asian-American population in the U. S. offers a unique model to study the interaction and relationships between visceral adiposity and adipose tissue distribution and beta cell function, insulin resistance, and atherosclerosis.
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J. Am. Coll. Cardiol. · Feb 2010
Risk of fatal arrhythmic events in long QT syndrome patients after syncope.
The aim of this study was to identify risk factors for fatal arrhythmias in long QT syndrome (LQTS) patients presenting with syncope. ⋯ Patients with syncope during beta-blocker therapy are at high risk of life-threatening events, and implantable cardioverter-defibrillator therapy should be considered in these patients. The risk of beta-blocker failure is highest in young children and in women.