Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Feb 2007
Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation.
This study sought to identify whether obesity and obstructive sleep apnea (OSA) independently predict incident atrial fibrillation/flutter (AF). ⋯ Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.
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J. Am. Coll. Cardiol. · Feb 2007
Total liquid ventilation provides ultra-fast cardioprotective cooling.
We tested whether total liquid ventilation (TLV) can be used to rapidly cool and protect the infarcting heart. ⋯ Total liquid ventilation can elicit rapid cardioprotective cooling during ischemia.
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J. Am. Coll. Cardiol. · Jan 2007
ReviewPlacebo and nocebo in cardiovascular health: implications for healthcare, research, and the doctor-patient relationship.
Despite treatments proven effective by sound study designs and robust end points, placebos remain integral to elicit effective medical care. The authenticity of the placebo response has been questioned, but placebos likely affect pain, functionality, symptoms, and quality of life. In cardiology, placebos influence disability, syncope, heart failure, atrial fibrillation, angina, and survival. ⋯ Imagine instead the future of healthcare relegated to a series of guidelines, tests, algorithms, procedures, and drugs without the human touch. Healthcare, rendered by a faceless, uncaring army of protocol aficionados, will miss an opportunity to deliver an effective placebo response. Wise placebo use can benefit patients and strengthen the medical profession.
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J. Am. Coll. Cardiol. · Jan 2007
Aortic root translocation plus arterial switch for transposition of the great arteries with left ventricular outflow tract obstruction: intermediate-term results.
The goal of our study was to report our intermediate-term results with aortic root translocation plus arterial switch for d-transposition of the great arteries with left ventricular outflow tract obstruction. ⋯ Aortic root autograft plus arterial switch procedure is a good option for the surgical management of infants and children with d-transposition of the great arteries and left ventricular outflow tract obstruction and results in a more anatomic repair compared with Rastelli operation. Intermediate-term results indicate good relief of left ventricular outflow tract obstruction and need for conduit replacement compares favorably with the Rastelli procedure for this lesion.