Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Sep 2003
Randomized Controlled Trial Multicenter Study Clinical TrialA randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis.
This study examined the effect of aspirin on the risk of embolic events in infective endocarditis (IE). ⋯ In endocarditis patients already receiving antibiotic treatment, the addition of aspirin does not appear to reduce the risk of embolic events and is likely associated with an increased risk of bleeding. Aspirin is not indicated in the early management of patients with IE.
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J. Am. Coll. Cardiol. · Sep 2003
Randomized Controlled Trial Clinical TrialGlucose-insulin-potassium infusion inpatients treated with primary angioplasty for acute myocardial infarction: the glucose-insulin-potassium study: a randomized trial.
In this study we considered the question of whether adjunction of glucose-insulin-potassium (GIK) infusion to primary coronary transluminal angioplasty (PTCA) is effective in patients with an acute myocardial infarction (MI). ⋯ Glucose-insulin-potassium infusion as adjunctive therapy to PTCA in acute MI did not result in a significant mortality reduction in all patients. In the subgroup of 856 patients without signs of HF, a significant reduction was seen. The effect of GIK infusion in patients with signs of HF (Killip class > or =2) at admission is uncertain.
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J. Am. Coll. Cardiol. · Sep 2003
Patterns of recurrence of congenital heart disease: an analysis of 6,640 consecutive pregnancies evaluated by detailed fetal echocardiography.
We sought to investigate the pattern of recurrence of congenital heart disease (CHD) where there is one or more affected first-degree relative. ⋯ The concordance rates of different types of CHD vary widely. Accurate diagnosis of the index case is essential for reliable counseling on patterns of recurrence. Minor CHD in the index case does not exclude more severe disease in recurrences. There appears to be significant under-referral for fetal echocardiography in paternal CHD.
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J. Am. Coll. Cardiol. · Sep 2003
Evaluation of pretest and exercise test scores to assess all-cause mortality in unselected patients presenting for exercise testing with symptoms of suspected coronary artery disease.
To determine how well recently developed multivariables scores assess for all-cause mortality in patients with suspected coronary disease presenting for exercise electrocardiography (ExECG). ⋯ Simple pretest and exercise scores risk-stratified patients with suspected coronary disease in accordance with published guidelines and better than the Duke treadmill score. These results extend to diabetics, inpatients, women, and patients on beta-blockers.
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J. Am. Coll. Cardiol. · Aug 2003
Comparative StudyEffect of body mass index on early outcomes in patients undergoing coronary artery bypass surgery.
This study sought to quantify the effect of body mass index (BMI) on early clinical outcomes following coronary artery bypass grafting (CABG). ⋯ Underweight patients undergoing CABG have a higher risk of death or complications than normal weight patients. Obesity does not affect the risk of perioperative death and other adverse outcomes compared to normal weight, yet obese patients appear less likely to be selected for surgery than normal weight patients.