Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Mar 2002
Low event rate for stress-only perfusion imaging in patients evaluated for chest pain.
We sought to demonstrate the safety of stress-only perfusion imaging among patients with low to medium probability of coronary disease being evaluated for chest pain. ⋯ These results support stress-only imaging in patients with low to medium probability for CAD as a safe, time- and cost-efficient imaging modality.
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J. Am. Coll. Cardiol. · Mar 2002
Randomized Controlled Trial Multicenter Study Clinical TrialThe impact of body mass index on short- and long-term outcomes inpatients undergoing coronary revascularization. Insights from the bypass angioplasty revascularization investigation (BARI).
We sought to investigate the impact of body mass index (BMI) on short- and long-term outcomes after initial revascularization with percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass graft surgery (CABG). ⋯ Body mass index appears to have a differential impact on short- and long-term outcomes after coronary revascularization. These results underscore the need for further research to identify factors responsible for the apparent short-term protective effect of a higher BMI in patients undergoing PTCA and to study the impact of weight reduction on the long-term survival of obese patients undergoing CABG.
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J. Am. Coll. Cardiol. · Mar 2002
Multicenter Study Clinical TrialInitial experience with an implantable cardioverter-defibrillator incorporating cardiac resynchronization therapy.
The purpose of this study was to evaluate an implantable cardioverter-defibrillator (ICD) incorporating biventricular pacing. ⋯ Incorporating biventricular pacing in an ICD is feasible and leads to an improvement of heart failure symptoms. Therefore, this therapy may become an option for patients who need ICD therapy in the presence of severe heart failure.
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J. Am. Coll. Cardiol. · Feb 2002
The impact of obesity on the short-term and long-term outcomes after percutaneous coronary intervention: the obesity paradox?
The purpose of this study was to assess the impact of body mass index (BMI) on the short- and long-term outcomes after percutaneous coronary intervention (PCI). ⋯ In patients with known CAD who undergo PCI, very lean patients (BMI <18.5) and those with BMI within the normal range are at the highest risk for in-hospital complications and cardiac death and for increased one-year mortality.
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J. Am. Coll. Cardiol. · Feb 2002
Heart failure in pressure overload hypertrophy. The relative roles of ventricular remodeling and myocardial dysfunction.
We sought to explore the relative contributions of ventricular remodeling and myocardial dysfunction to heart failure in pressure overload hypertrophy (POH). ⋯ The two POH groups differed primarily in their remodeling process, which led to a chronically compensated state in one group and to heart failure in the other. Hence, heart failure in POH is more closely related to deleterious LV remodeling than to depressed myocardial function.