Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jan 1998
Comparative StudyOutcome with calcium channel antagonists after myocardial infarction: a community-based study.
We sought to estimate the risk of death and recurrent myocardial infarction associated with the use of calcium antagonists after myocardial infarction in a population-based cohort study. ⋯ These results are consistent with randomized trial data showing benefit from beta-blockers after myocardial infarction and no effect on the risk of recurrent myocardial infarction and death with the use of calcium antagonists. Comparisons between beta-blockers and calcium antagonists favor beta-blockers because of the beneficial effects of beta-blockers and not because of adverse effects of calcium antagonists.
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J. Am. Coll. Cardiol. · Dec 1997
Multicenter StudyManagement of acute myocardial infarction in intensive care units in 1995: a nationwide French survey of practice and early hospital results.
This survey sought to determine actual practices in the management of acute myocardial infarction on a nationwide scale. ⋯ This survey shows that the results of therapeutic trials have largely translated to clinical practice, resulting in improved early outcome compared with the early 1980s. However, continuous efforts should be made to shorten the time delay before hospital admission and to increase the proportion of elderly patients receiving reperfusion therapy.
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J. Am. Coll. Cardiol. · Dec 1997
Effects of chronic hypoxemia on chemosensitivity in patients with univentricular heart.
We sought to compare the arterial blood gas chemosensitivity in relation to exercise ventilatory response in patients with univentricular heart and cyanosis and in patients with univentricular heart and Fontan-type circulation without cyanosis. ⋯ Hypoxic chemosensitivity is blunted in patients with univentricular heart and cyanosis and does not determine the exercise ventilatory response. CO2 elimination appears more important. The blunting of hypoxic chemosensitivity is reversible once chronic hypoxemia is relieved, as evident in the Fontan group.
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J. Am. Coll. Cardiol. · Nov 1997
Out-of-hospital cardiac arrest in the 1990's: a population-based study in the Maastricht area on incidence, characteristics and survival.
We sought to describe the incidence, characteristics and survival of out-of-hospital sudden cardiac arrest (SCA) in the Maastricht area of The Netherlands. ⋯ The majority of victims of SCA cannot be identified before the event. Sudden cardiac arrest usually occurs at home, and the survival of those with a witnessed SCA at home was low compared with that outside the home, indicating the necessity of optimizing out-of-hospital resuscitation, especially in the at-home situation.
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J. Am. Coll. Cardiol. · Nov 1997
Serial changes in response of hibernating myocardium to inotropic stimulation after revascularization: a dobutamine echocardiographic study.
We sought to evaluate the serial changes in the response of the hibernating myocardium to dobutamine stimulation after revascularization. ⋯ In myocardial hibernation, the majority of recovery of rest function occurs early after revascularization. Although patients who recover rest function show the most marked improvement in wall motion during DSE, those without recovery of rest function also have improved function during DSE, particularly when there is evidence of ischemia before revascularization.