Journal of the American College of Cardiology
The most recent articles from:
J. Am. Coll. Cardiol.
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J. Am. Coll. Cardiol. · Dec 2014
Observational StudyIs epinephrine during cardiac arrest associated with worse outcomes in resuscitated patients?
Although epinephrine is essential for successful return of spontaneous circulation (ROSC), the influence of this drug on recovery during the post-cardiac arrest phase is debatable. ⋯ In this large cohort of patients who achieved ROSC, pre-hospital use of epinephrine was consistently associated with a lower chance of survival, an association that showed a dose effect and persisted despite post-resuscitation interventions. These findings suggest that additional studies to determine if and how epinephrine may provide long-term functional survival benefit are needed.