Journal of hypertension
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Journal of hypertension · Nov 2011
Urinary renin, but not angiotensinogen or aldosterone, reflects the renal renin-angiotensin-aldosterone system activity and the efficacy of renin-angiotensin-aldosterone system blockade in the kidney.
To study which renin-angiotensin-aldosterone system (RAAS) component best reflects renal RAAS activity. ⋯ The increased urinary renin levels in diabetes and the decreased urinary renin levels following RAAS blockade, occurring independently of changes in plasma renin, reflect the activated renal RAAS in diabetes and the success of RAAS blockade in the kidney, respectively. Urinary renin, therefore, more closely reflects renal RAAS activity than urinary angiotensinogen or aldosterone.
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Journal of hypertension · Aug 2011
Comparative StudyDistinct role of electrocardiographic criteria in echocardiographic diagnosis of left ventricular hypertrophy according to age, in the general population: the Ikaria Study.
The age-dependent performance of electrocardiographic (ECG) criteria was examined for left ventricular hypertrophy (LVH) prediction. ⋯ Age should be taken into consideration in selection of appropriate ECG criteria for LVH detection. Indexation of left ventricular mass differentiates the diagnostic ability of ECG criteria, especially in older patients.
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Journal of hypertension · Jul 2011
Prevalence, awareness, treatment, control, and risk factors associated with hypertension in urban adults from 33 communities of China: the CHPSNE study.
To assess the prevalence, awareness, treatment, and control of hypertension and their associated factors in an urban Chinese population. ⋯ Hypertension is highly prevalent in the urban population of China, and the effects of being overweight/obesity on hypertension were much larger than any other examined factors. The percentage of hypertensive patients aware of their condition, receiving proper treatment, and keeping their hypertension under control is unacceptably low.
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Journal of hypertension · Jul 2011
Low-frequency fluctuations in heart rate, cardiac output and mean arterial pressure in humans: what are the physiological relationships?
Cardiovascular variability is a complex physiological phenomenon associated with the outcome of cardiovascular diseases. Blood pressure oscillations may cause cardiovascular complications, which, however, are also claimed to have antihypertensive effects. The physiological understanding is limited. This study evaluates whether oscillations in heart rate (HR) and cardiac output (CO) buffer fluctuations at approximately 0.1 Hz in arterial blood pressure (Mayer waves). ⋯ TPR oscillations produce fluctuations in MAP at 0.1 Hz. HRV produces CO variations, but CO variations do not efficiently buffer MAP variations during supine rest and mild ortostasis. Both feedback and feedforward mechanisms are responsible for the interaction between HR and MAP.