Journal of hypertension
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Journal of hypertension · May 2004
Effects of long-term intake of edible oils on hypertension and myocardial and aortic remodelling in spontaneously hypertensive rats.
The nature of dietary lipid intake contributes to blood pressure control. ⋯ The most beneficial cardiac and aortic structural effects occurred in the fish-oil group. Both canola oil and palm oil were also effective in reducing blood pressure, favouring myocardial remodelling, although they produced contrasting effects with regard to aorta wall structure. Soybean oil and olive oil had mild effects on myocardial and aortic structure.
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Journal of hypertension · Jan 2004
Randomized Controlled Trial Comparative Study Clinical TrialBarriers to management of cardiovascular risk in a low-resource setting using hypertension as an entry point.
Assess capacity of health-care facilities in a low-resource setting to implement the absolute risk approach for assessment of cardiovascular risk in hypertensive patients and effective management of hypertension. ⋯ If the absolute risk approach for assessment of risk and effective management of hypertension is to be implemented in low-resource settings, appropriate policy measures need to be taken to improve the competency of health-care providers, to provide basic laboratory facilities and to develop affordable financing mechanisms.
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Journal of hypertension · Jan 2004
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialIntervention at lower blood pressure levels to achieve target goals in type 2 diabetes: PRADID (PResión Arterial en DIabéticos tipo Dos) study.
Arterial hypertension greatly increases the risk of cardiovascular disease, renal insufficiency, and retinopathy in patients with type 2 diabetes. Epidemiological studies all document a reduced risk for the aforementioned consequences at a blood pressure (BP) lower than 130/80 mmHg. For this reason, lower target BPs are recommended by recent guidelines committees. A lower threshold BP for treatment, also proposed in guidelines, could facilitate the attainment of the recommended target BP. However, little data exist on the efficacy and safety of starting pharmacological therapy in type 2 diabetic patients exhibiting high-normal BP (HNBP) or the first stage of isolated systolic hypertension previously considered as borderline isolated systolic hypertension (BISH). ⋯ Antihypertensive treatment is more effective than placebo for controlling SBP and DBP in previously untreated participants with type 2 diabetes exhibiting low threshold BP values. Combination therapy with verapamil SR/trandolapril was more effective than trandolapril alone for controlling DBP.
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Journal of hypertension · Dec 2003
Randomized Controlled Trial Comparative Study Clinical TrialSystolic blood pressure variability as a risk factor for stroke and cardiovascular mortality in the elderly hypertensive population.
To investigate whether baseline systolic blood pressure variability was a risk factor for stroke, cardiovascular mortality or cardiac events during the Syst-Eur trial. ⋯ In the placebo group, but not the active treatment group, increased night-time systolic blood pressure variability on admission to the Syst-Eur trial was an independent risk factor for stroke during the trial.