The American journal of emergency medicine
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Esmolol is a highly selective beta 1 receptor blocker with various effects such as slowing heart rate, lowering blood pressure and reducing myocardial oxygen consumption. However, few studies have reported the use of beta blockers in sepsis with multiple organ dysfunctions. This study aimed to investigate the effects of esmolol on reducing apoptosis and inflammation in early sepsis rats with abdominal infection. ⋯ The administration of esmolol in early sepsis may reduce inflammation, inhibit apoptosis and protect key organs.
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Case Reports
Never say never: Identification of acute pulmonary embolism on non-contrast computed tomography imaging.
Acute undifferentiated illness remains a critical challenge for the emergency physician. The diagnostic evaluation and treatment decisions on such severely ill patients often needs to be made in an expedited fashion. Situations occur wherein the ideal or recommended workup is not always feasible due to time or patient specific factors. We present two cases of patients with undifferentiated acute illness who had undergone non-contrast CT (computed tomography) scanning and subsequently had central pulmonary embolism identified upon careful review of their CT studies.
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Review Meta Analysis
Effect of paracetamol (acetaminophen) on body temperature in acute stroke: A meta-analysis.
The objective of this study was to assess the efficacy of paracetamol (acetaminophen) on body temperature in acute stroke. ⋯ Acetaminophen showed some capability to decrease body temperature for acute stroke. Acetaminophen could not improve functional outcome and reduce adverse events of patients with acute stroke.