The American journal of emergency medicine
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Comparative Study Observational Study
Temporal trends in out-of-hospital cardiac arrest outcomes in men and women from 2008 to 2015: A national observational study.
We compared the temporal trends in survival and neurological outcomes after out-of-hospital cardiac arrest (OHCA) in men and women. ⋯ The outcomes of OHCA improved in both sexes during the study period. The degree of improvement in outcomes was higher in men than in women.
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Review Meta Analysis
Effects of morphine on P2Y12 platelet inhibitors in patients with acute myocardial infarction: A meta-analysis.
To explore the effects of morphine on P2Y12 platelet inhibitors in patients with acute myocardial infarction (AMI). ⋯ Morphine effectively suppresses the inhibition effect of P2Y12 platelet inhibitors in patients with AMI.
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Laboratory testing is commonly performed in patients with COVID-19. Each of the laboratory parameters has potential value for risk stratification and prediction of COVID-19 outcomes. This systematic review and meta-analysis aimed to evaluate the difference between these parameters in severe and nonsevere disease and to provide the optimal cutoff value for predicting severe disease. ⋯ This meta-analysis suggests elevated procalcitonin, CRP, D-dimer, and LDH and decreased albumin can be used for predicting severe outcomes in COVID-19.
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Randomized Controlled Trial
Isopropyl alcohol nasal inhalation for nausea in the triage of an adult emergency department.
Nausea and vomiting (N&V) are among the most common complaints in the emergency department (ED). However, low acuity is assigned to most of these patients at the triage, and waiting for long hours without medication decreases patient safety and satisfaction. We aimed to compare the inhalation of isopropyl alcohol (IPA) with placebo (P) to treat nausea at the triage area of an ED. ⋯ In this study, IPA was significantly more effective than P for N&V at the triage. Moreover, patients in the IPA group had less need for rescue treatment.
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Barrier enclosure devices were introduced to protect against infectious disease transmission during aerosol generating medical procedures (AGMP). Recent discussion in the medical community has led to new designs and adoption despite limited evidence. A scoping review was conducted to characterize devices being used and their performance. ⋯ While use of various barrier enclosure devices has become widespread during this pandemic, objective data of efficacy, efficiency, and usability is limited. Further controlled studies are required before adoption into routine clinical practice.