The American journal of emergency medicine
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Review Meta Analysis Comparative Study
Tenecteplase for thrombolysis in stroke patients: Systematic review with meta-analysis.
Alteplase is an approved treatment for acute ischemic stroke. Tenecteplase is a genetically modified form of alteplase, with lower cost and a more favourable pharmacokinetic profile allowing bolus injection. The aim of this study was to compare both drugs in adult patients with acute ischemic stroke undergoing thrombolysis. ⋯ Tenecteplase is an alternative to alteplase for stroke thrombolysis, with lower cost and a more favourable pharmacokinetic profile.
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Multicenter Study Observational Study
Frequency of safety net errors in the emergency department: Effect of patient handoffs.
The objective of this study was to determine physician awareness of abnormal vital signs and key clinical interventions (oxygen provision, intravenous access) in the emergency department, and to measure the effect of patient handoffs on this awareness. ⋯ Emergency physicians make frequent errors regarding awareness of their patients' vital signs, oxygen and vascular status and patient handoffs are associated with an increased frequency of such errors.
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Multicenter Study
Association of air temperature with pediatric intussusception in northeastern China: A 10-year retrospective study.
The aim of this study was to determine whether an association existed between intussusception and air temperature. ⋯ Monthly PPI cases were positively associated with monthly mean temperature in Shenyang. The incidence of intussusception shows a seasonal trend, with a peak in summer (May to July).